REGULAR EXERCİSE, L-CARNİTİNE AND DİABETES TYPE II

Abstract

Physical activity, regular exercise and physical fitness affect human life to live healthier and longer than normal. Physical activity deficiency is now quite common in the adult and elderly population. Combined with the increasing inactivity of the needs of most business sectors in a sitting position or the prolonged time at the computer, it shortens the physical activity of individuals. This physical activation deficiency in individuals is also of great importance in health problems caused by inactivity. One of the biggest health problems caused by lack of physical activity is diabetes type II disease. Diabetes disease is a metabolic disease caused by insufficient insulin secretion of the pancreas or impaired response of tissues to insulin, affecting protein, fat and carbohydrate metabolism. The 
most important sign of the disease is hyperglycemia. L-carnitine is a derivative of lysine and methionine amino acids. Carnitine is first synthesized in the liver and kidneys in our body, then it can be transferred to other tissues. L Carnitine increases non-oxidative glucose excretion and increases the effect of carnitine on glycogen storage in euglycemic hyperinsulinemic conditions in healthy people and type 2 patients with diabetes. L-Carnitine administration improves insulin-stimulated glucose excretion and shows that the metabolite has worked at the interface between fatty acid metabolism and glucose metabolism. As a result, regular exercise and physical fitness of people are in good condition, significantly preventing the risk of people getting type II diabetes and also 
eliminating the risk factors associated with type II diabetes. The use of L-carnitine positively affects the course of the disease in people with type II diabetes. As a result of these results, the use of L-Carnitine in diabetes type 2 patients may be recommended in combination with physical activity and regular exercise under expert control.